The front of a man's sperm must join to the egg's exterior before it may fertilize a woman's egg. Once entered, the sperm pushes through the egg's external layer to the cytoplasm, where fertilization occurs.
For a variety of purposes, sperm may be unable to enter the outer layer. The sperm may be unable to swim, or the egg's outer layer may be thick or difficult to penetrate. In some circumstances, intracytoplasmic sperm injection (ICSI) can be used in conjunction with IVF to aid in fertilizing the egg. A single sperm is inserted directly into the cytoplasm of the egg during ICSI.
IVF can be used to fertilize an egg in two ways: conventional and ICSI. When one of the sperm enters the cytoplasm of the egg, it fertilizes it. A small needle called a micropipette is used to inject a single sperm into the centre of the egg during the ICSI procedure. After fertilization, the fertilised egg (now termed an embryo) matures in a lab for 1 to 5 days before being transferred to the woman's uterus.
The lady will need to take fertility medicine to increase egg production in the ovaries, like regular IVF. During this time, the doctor will keep an eye on the eggs' progress. When the egg is set to be extorted, the ICSI process is carried out.
The man must produce a sperm specimen by ejaculating into a cup, or the sperm must be surgically extracted. The sperm can be removed in several different methods. The sperm retrieval method may be conducted sooner in some situations, and the sperm may be frozen.
The semen sample is then cleansed, and a single sperm is extracted. With an excellent hollow needle, this is then inserted into an egg. The sperm does not have to swim through the cervical solution because it is injected immediately. It can take up to 24 hours for sperm to fertilize an egg and form an embryo.
The fertilised embryos are stored in a laboratory for up to 6 days after fertilization. During this stage, they are watched for signs of development and growth. The fertilised embryos will not all be transported to the uterus of the woman. As a result, this phase is critical for selecting the healthiest and most viable sources.
One or two embryos are chosen and transferred to the woman's womb using an ultrasound-guided catheter once the embryo has reached a particular stage of development. This can happen two days after conception or five days afterward.
ICSI aids in the treatment of infertility issues such as:
Artificial insemination (intrauterine insemination [IUI]) is impossible since the male spouse generates low sperm.
It's possible that the sperm won't migrate usually.
The sperm have problems adhering to the egg.
Sperm may not be able to leave the male conceptive system due to a blockage.
50% to 80% of eggs are prepared using ICSI. However, the following issues may arise during or after the ICSI procedure:
It's possible that some or all of the eggs will be harmed.
Even after being injected with sperm, the egg may not develop into an embryo.
The embryo may stop growing.
After fertilization, a couple's chances of having a single child, twins, or triplets are the same whether they use IVF with or without ICSI.
If a woman becomes pregnant quickly, her kid has a 1.5 percent to 3% chance of having a severe birth problem. ICSI has the same risk of birth abnormalities as IVF, but it is more significant than a spontaneous idea.
The slightly increased risk of birth abnormalities may be attributed to infertility rather than the procedures employed to overcome it.
ICSI has been linked to Beckwith-Wiedemann syndrome, Angelman syndrome, and sex chromosomal abnormalities, among other diseases. They are thought to occur in less than 1% of children born using this method.
Infertility can be caused by a variety of factors, some of which are inherited. Male infants conceived through ICSI, for example, may face the same infertility challenges as their dads.
Get in touch with Dr. Prachi Benara for all the treatments related to ICSI, as she has a decade + experience of being an infertility specialist.
For unplanned pregnancy plans Contact Us